The landmark James Pharmacy building is fully occupied, operating as the James Pharmacy Bed & Breakfast and restaurant on vibrant Main Street, Old Saybrook. Anna James, daughter of a slave and the first African American female pharmacist owned and operated the iconic pharmacy for decades, residing upstairs. Her niece, noted novelist Anna Petry, was born here and assisted Miss James. The main floor restaurant retains the historic pharmacy built-ins and soda fountain. Arched glass windows offer diners a Main Street view. Three B&B guest rooms are well appointed and upscale, each with a fully renovated bath and a gas fireplace. Max. occupancy 6 guests. Innkeeper quarters are on the main level. The building underwent extensive updates and renovations, bringing it to current standards while preserving its beauty and historic architecture. Exterior painting two sides slated for October. A full basement houses mechanicals, exceptional storage and clean storage. Old Saybrook is a popular weekend destination. Sidewalks access a plethora of restaurants, shops, The Kate cultural arts center and Saybrook Station just 2 hours from NY/Boston. Find exceptional beaches, boating, Fenwick or Fox Hopyard Golf a short drive. A vibrant Chamber of Commerce works tirelessly ensuring Old Saybrook businesses have the support they need with Main Street events throughout the year. Limited area lodging ensures the James Pharmacy Bed & Breakfast and restaurant are an option with provenance year-round.